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Stenotrophomonas maltophilia endocarditis

Nancy F Crum1, Gregory C Utz, Mark R Wallace

  • 1Department of Internal Medicine, Infectious Diseases Division, Naval Medical Center San Diego, San Diego CA 92134, USA. nfcrum@nmcsd.med.navy.mil

Scandinavian Journal of Infectious Diseases
|February 18, 2003
PubMed

Insights

Stenotrophomonas maltophilia endocarditis is rare but serious, particularly in immunocompromised patients. Early treatment with trimethoprim-sulfamethoxazole and device removal is crucial for better outcomes.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Cardiology

Background:

  • Stenotrophomonas maltophilia is a Gram-negative bacillus increasingly implicated in nosocomial infections.
  • Endocarditis caused by S. maltophilia is an uncommon but severe clinical manifestation.
  • Immunocompromised patients are particularly vulnerable to severe S. maltophilia infections.

Observation:

  • This case report details S. maltophilia endocarditis in a patient with a central venous catheter.
  • The clinical presentation and management of this rare condition are described.
  • A review of existing literature on Stenotrophomonas endocarditis is presented.

Findings:

  • S. maltophilia poses a significant risk for endocarditis, especially in patients with indwelling devices.
  • The review highlights the limited but critical data on Stenotrophomonas endocarditis.
  • Early diagnosis and intervention are key to managing this infection.

Implications:

  • Prompt antibiotic therapy, including trimethoprim-sulfamethoxazole and a second agent, is vital.
  • Removal of prosthetic devices, such as central venous catheters, is recommended.
  • Aggressive management strategies are necessary due to the high morbidity and mortality associated with S. maltophilia endocarditis.

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