[Antibodies in venereal sarcoma in dogs]

Neoplastic cell suspensions prepared from fourteen spontaneous and three transplanted vereal sarcomas of the dog were studied by microcytotoxicity and immunofluorescence tests. Serum and cell-surface antibodies were found in all cases. These antibodies were not capable of activating canine complement. Most likely these antibodies are not cytotoxic in vivo, but rather act by enhancing tumor growth.