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[Experimental study of the effect of glucosamine hydrochloride on metabolic and repair processes in connective tissue
I A Zupanets1, N V Bezdetko, N V Dedukh
1Clinical Pharmacy Department, National Pharmaceutical Academy of Ukraine, ul. Pushkinskaya 53, Kharkov 61002, Ukraine.
Abstract:
The effects of glucosamine hydrochloride on the metabolic and repair processes were studied on a model of post-traumatic osteoarthrosis in the articular cartilage and on a model of post-traumatic keratitis in the cornea. The administration of glucosamine hydrochloride stimulated repair and favored inhibition of dystrophic post-traumatic processes in the connective-tissue structures. It is suggested that a probable mechanism of the drug action consists in stimulation of the synthesis of glucosaminoglycanes and collagen.
