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Cyclization of aryl silanes with unexpected retention of silicon
Stephen Philip Fearnley1, Michael W Tidwell
1Department of Chemistry and Physics, Lamar University, P.O. Box 10022, Beaumont, Texas 77710, USA. fearnleysp@hal.lamar.edu
Organic Letters
|February 26, 2003
Abstract:
[formula: see text] Intramolecular Friedel-Crafts cyclization of 2-O-benzyl ethers at a model pyranose acetal is activated by incorporation of a trimethylsilyl group, albeit via unexpected, presumably steric means.