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Perioperative infusions in paediatric patients: rationale for using Ringer-lactate solution with low dextrose
M-P Berleur1, A Dahan, I Murat
1Agence générale des équipements et produits de santé, Etablissement pharmaceutique des hôpitaux de Paris, UF Affaires réglementaries, Paris, France. marie-pierre.berleur@eps.ap-hop
Journal of Clinical Pharmacy and Therapeutics
|February 28, 2003
Summary
Ringer-lactate solution with dextrose is suitable for pediatric perioperative fluid therapy. Further research is needed for optimal electrolyte and dextrose management in pediatric surgery.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Intravenous Fluid Therapy
Background:
- Intravenous (i.v.) fluid and water are essential during surgery.
- Sodium is crucial, necessitating normonatremic solutions to prevent hyponatremia.
- Limited data exist on other electrolytes' roles in pediatric surgical fluid therapy.
Purpose of the Study:
- To evaluate the efficacy of Ringer-lactate solution with 0.9% dextrose for pediatric perioperative fluid therapy.
- To review current literature on fluid and electrolyte management in pediatric surgical patients.
- To identify areas for improvement in clinical guidelines for pediatric surgical fluid therapy.
Main Methods:
- Literature review of studies on Ringer-lactate solution with dextrose in pediatric patients.
- Analysis of four clinical trials assessing 0.9% or 1% dextrose concentrations.
- Examination of fluid and electrolyte requirements during pediatric surgery.
Main Results:
- Ringer-lactate solution with 0.9% or 1% dextrose appears appropriate for routine perioperative infusion in pediatric patients.
- The need for i.v. fluids, water, and sodium is well-established.
- Dextrose requirements remain a topic of debate, balancing hypoglycemia and hyperglycemia risks.
Conclusions:
- Ringer-lactate solution with dextrose is a viable option for pediatric perioperative fluid management.
- Consensus clinical guidelines for electrolyte infusions in pediatric surgery are recommended.
- Further research into optimal fluid and electrolyte strategies in pediatric surgery is warranted.