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Updated: Jul 13, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
Published on: May 2, 2013
False-positive reaction to VDRL test with prozone phenomena. Association with lymphosarcoma
1Venereal Disease Branch, Communicable Disease Center, Public Health Service, Department of Public Health, San Francisco, USA.
Abstract:
A patient with lymphosarcoma had a VDRL test reactive at 1:256. A prozone phenomenon was also present. The nontreponemal test result was shown to be a false-positive reaction by nonreactive Treponema pallidum immobilization and fluorescent treponemal antibody absorption tests. High-titer serologic tests for syphilis are uncommon, and prozone reactions are previously unrecorded in the false-positive reactor.
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