Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Distinguishing starvation from cachexia.

David R Thomas1

  • 1Division of Geriatric Medicine, Saint Louis Health Sciences Center, 1402 South Grand Boulevard M238, Saint Louis, MO 63140, USA. thomasdr@slu.edu

Clinics in Geriatric Medicine
|March 1, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Nuclear Transporter Transportin-3 Functions Under Oxidative Stress.

Cells·2026
Same author

A new taxonomy of social support: Clarifying supportive behaviours and measures.

Journal of health psychology·2026
Same author

Intralysosomal pathogens differentially influence the proteolytic potential of their niche.

Infection and immunity·2025
Same author

Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success.

Nature communications·2025
Same author

Coxiella burnetii protein CBU2016 supports CCV expansion.

Pathogens and disease·2024
Same author

<i>Coxiella</i> co-opts the Glutathione Peroxidase 4 to protect the host cell from oxidative stress-induced cell death.

Proceedings of the National Academy of Sciences of the United States of America·2023
Same journal

Cardiovascular Prevention in Older Adults: From Estimation to Treatment.

Clinics in geriatric medicine·2026
Same journal

Preventive Cardiology for the Clinically Complex Older Adult.

Clinics in geriatric medicine·2026
Same journal

A Preventive Neurology Perspective on Promoting Brain Health and Preventing Cardiovascular Disease.

Clinics in geriatric medicine·2026
Same journal

Secondary Prevention in Older Adults: Putting It All Together.

Clinics in geriatric medicine·2026
Same journal

Primary Prevention in Older Adults: Putting It All Together.

Clinics in geriatric medicine·2026
Same journal

Managing Bleeding Risk in Older Adults: Antithrombotics and Anticoagulants.

Clinics in geriatric medicine·2026
See all related articles

Refeeding reverses starvation but is less effective for cachexia in ill adults. Distinguishing between these conditions is crucial for effective nutritional interventions and improving patient outcomes in clinical trials.

Area of Science:

  • Clinical Nutrition
  • Metabolic Disorders
  • Patient Outcomes

Background:

  • Ill adults often show a poor response to hypercaloric feeding.
  • This poor response may stem from a failure to differentiate between cachexia and starvation.
  • Cachexia and starvation have distinct responses to nutritional support.

Purpose of the Study:

  • To highlight the importance of distinguishing cachexia from starvation in ill adults.
  • To explain the differential response to refeeding in these two conditions.
  • To provide insights into the ineffectiveness of nutritional interventions in cachectic patients.

Main Methods:

  • Comparative analysis of starvation and cachexia.
  • Review of clinical trial data on nutritional interventions.

Related Experiment Videos

  • Discussion of refeeding efficacy in different catabolic states.

    • Main Results:

    • Refeeding effectively reverses starvation.
    • Refeeding is less effective in treating cachexia.
    • The ineffectiveness of refeeding in cachexia may explain poor clinical trial results.

    Conclusions:

    • Accurate diagnosis of cachexia versus starvation is critical for effective treatment.
    • Failure to distinguish these conditions leads to suboptimal nutritional strategies.
    • Understanding these differences can improve outcomes for ill adults receiving nutritional support.