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Highly efficient deprotection of aromatic acetals under neutral conditions using beta-cyclodextrin in water
N Srilakshmi Krishnaveni1, K Surendra, M Arjun Reddy
1Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India ramaraok@iict.res.in
The Journal of Organic Chemistry
|March 1, 2003
Abstract:
Aromatic acetals have been deprotected to the corresponding aldehydes under biomimetic conditions for the first time using beta-cyclodextrin in water under neutral conditions, thereby overcoming many of the drawbacks associated with earlier methodologies. This method, apart from being simple with regard to recycling of the catalyst, also has the potential for industrial applications.