Cutaneous manifestations as initial presentation of Waldenstrom's macroglobulinemia

Waldenstr m's Macroglobulinemia is a rare chronic lymphoproliferative disease. Clinical manifestations include usually weakness, weight loss, lymphadenopathy. Lung, kidney, heart, nervous system or bone may be involved. Cutaneous manifestations are unusual and misunderstood. Two different types of cutaneous lesions are described: non-specific and specific. They may reveal the disease or appear during the course of it. We report a case of a Waldenstr m's Macroglobulinemia with cutaneous involvement.