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Spontaneous internal carotid artery dissection and alpha-1-antitrypsin deficiency
C Konrad1, D G Nabavi, R Junker
1Department of Neurology, University of Muenster, Muenster, Germany. konradc@uni-muenster.de
Acta Neurologica Scandinavica
|March 5, 2003
Abstract:
Spontaneous cervical arterial dissection is an important cause of juvenile stroke. However, etiopathology and genetic background remain poorly understood. We report on a 45-year-old-male patient with homozygous alpha-1-antitrypsin (alpha-1-AT) deficiency in whom internal carotid artery dissection occurred in the absence of any other known risk factors. The relevance of alpha-1-AT deficiency for spontaneous cervical arterial dissections is discussed.