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Published on: November 7, 2018
Familial clustering of hepatitis B infection: study of a family
Govind Verma1, Prakash Dalai, Mukta Bapat
1Department of Gastroenterology, Seth G S Medical College and K E M Hospital, Mumbai 400 012.
Abstract:
Familial clustering of hepatitis B virus infection has been reported infrequently. We report a family of 27 members, where 13 members were HBsAg-positive. This included 7 of 10 members in one linear family across four generations. Nine subjects who were tested were HBeAg-negative. Of these nine, three subjects had elevated ALT; histology in one of them showed activity index <3. One subject received lamivudine therapy elsewhere; ALT levels returned to normal in two months.
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