Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microarray workshop on aging.

Prakash N Nair1, Tamara Golden, Simon Melov

  • 1Department of Physiology and South Texas Centers for Biology in Medicine, University of Texas Health Science Center in San Antonio, 15355 Lambda Drive, San Antonio, TX 78245, USA. nairp@uthscsa.edu <nairp@uthscsa.edu>

Mechanisms of Ageing and Development
|March 6, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single-nucleus profiling reveals age-associated remodeling opposed by parity in the postmenopausal human ovary.

bioRxiv : the preprint server for biology·2026
Same author

Exceptional Longevity Modifying Allele APOE2 Promotes DNA Signaling Pathways Resisting Cellular Senescence in Human Neurons.

Aging cell·2026
Same author

Senescent Schwann cells as therapeutic targets in nerve regeneration and peripheral neuropathies.

Trends in molecular medicine·2026
Same author

Senescence-Linked Fibrosis in the Aging Human Ovary Revealed by p16-Based Histological Profiling and Spatial Transcriptomics.

Research square·2026
Same author

CD38 Inhibition Ameliorates Age-Related CognitiveDecline via a Choroid Plexus-Cerebrospinal Fluid-Hippocampus Axis.

Research square·2026
Same author

Senescence-Linked Fibrosis in the Aging Human Ovary Revealed by p16-Based Histological Profiling and Spatial Transcriptomics.

bioRxiv : the preprint server for biology·2025
Same journal

Human sex-specific hormone effects on cerebrovascular health in males and females.

Mechanisms of ageing and development·2026
Same journal

HTZ-1/H2A.Z expression sustains transcriptional programs that regulate Caenorhabditis elegans lifespan.

Mechanisms of ageing and development·2026
Same journal

PCSK9 promotes aging-related cardiac calcification by inducing osteogenic differentiation of cardiac fibroblasts.

Mechanisms of ageing and development·2026
Same journal

Distinct post-infectious TLR2 immune remodeling in COVID-19-recovered centenarians.

Mechanisms of ageing and development·2026
Same journal

Senescence-associated tertiary lymphoid structures in Sjögren's disease model nishiura mice.

Mechanisms of ageing and development·2026
Same journal

Aging-driven reprogramming of CD34⁺ hematopoietic stem cells in leukemogenesis: Mechanisms and therapeutic implications.

Mechanisms of ageing and development·2026
See all related articles

Microarray technology offers exciting potential for aging research but requires careful methodology and statistical analysis. Addressing these details is crucial for understanding aging and related diseases.

Area of Science:

  • Genomics and aging research
  • Functional genomics applications

Background:

  • Microarrays provide powerful tools for studying gene expression in aging.
  • Understanding molecular mechanisms of aging and age-related diseases is a key challenge.

Framework:

  • The report summarizes discussions from a microarray workshop on aging.
  • Key topics included technical and statistical considerations for microarray experiments.

Implementation:

  • Discussions covered array printing, RNA isolation, cDNA labeling, and hybridization.
  • Optimal experimental design and robust statistical analysis were emphasized.
  • Laser capture microdissection for complex tissue analysis was also addressed.

Implications:

Related Experiment Videos

  • Rigorous implementation of microarray technology is essential for advancing aging science.
  • Improved methods will enhance the discovery of aging mechanisms and disease insights.