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Updated: Sep 27, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
[Diagnosis of stroke--an update]
1Neurologische Abteilung, Landes-Nervenklinik Wagner-Jauregg, Wagner-Jauregg-Weg 15, A-4020 Linz. Franz.Aichner@wj.lkh.ooe.gv.at
Insights
Accurate stroke diagnosis requires advanced imaging like CT or MRI to distinguish between ischemic stroke and hemorrhage. Non-invasive vascular imaging, such as ultrasound and MR angiography, aids in diagnosis and prognosis.
Area of Science:
- Neurology
- Radiology
- Cardiology
Background:
- Common stroke causes include atherothrombosis, small vessel disease, cardioembolism, hypertensive hemorrhage, and subarachnoid hemorrhage.
- Clinical diagnosis of stroke faces challenges in confirming stroke presence, differentiating infarct from hemorrhage, and localizing lesions.
Purpose of the Study:
- To summarize the diagnostic tools available for stroke assessment.
- To provide an overview of clinically reliable and relevant diagnostic measures for stroke.
Main Methods:
- Clinical assessment and scoring methods.
- Brain computed tomography (CT) and magnetic resonance imaging (MRI) for stroke type differentiation.
- Ultrasound and magnetic resonance angiography (MRA) for vascular diagnosis.
- Catheter angiography for specific cases (subarachnoid hemorrhage, prognosis).
- Echocardiography (transthoracic and transesophageal) for cardioembolic source identification.
Main Results:
- No clinical scoring method reliably differentiates ischemic stroke from primary intracerebral hemorrhage; neuroimaging is essential.
- Ultrasound and MRA are sensitive, non-invasive, and complementary for vascular diagnosis.
- Cardioembolic stroke diagnosis relies on identifying an embolic source, present in ~30% of ischemic strokes, with echocardiography aiding detection.
- Transesophageal echocardiography offers more anatomical detail than transthoracic echocardiography but its impact on clinical decision-making is debated.
Conclusions:
- Neuroimaging (CT/MRI) is crucial for accurate stroke diagnosis and differentiation.
- Non-invasive vascular imaging techniques are valuable for diagnosis and prognosis.
- Identifying cardioembolic sources via echocardiography is important for specific stroke types.
Abstract:
In practical day-to-day terms, most patients have one of the common causes of stroke: ischemic stroke caused by the complications of atherothrombosis, intracranial small Vessel disease, embolism from the heart, primary intracerebral hemorrhage caused by hypertension, or subarachnoid hemorrhage as a result of a ruptured saccular aneurysm. There are three issues to be considered in assessing the reliability of the clinical diagnosis of stroke: the diagnosis of stroke itself: is it a stroke or not; whether the stroke is caused by an infarct or a hemorrhage and particular in ischemic stroke the site and size of the lesion (anterior vs. posterior circulation, lacunar vs. cortical, etc.) No clinical scoring method can differentiate with absolute reliability ischemic stroke from primary intracerebral hemorrhage. To do this brain computed tomography or magnetic resonance imaging is required. For vascular diagnosis ultrasound and magnetic resonance angiography are ideal and complementary non-invasive techniques. Both have no risks and are reasonably sensitive. Catheterangiography is only reserved for patients with subarachnoid hemorrhage with a view to surgical or endovascular treatment or in exceptional cases to establish a more firm prognosis. The diagnosis of ischemic stroke caused by embolism from the heart can only be considered at all if there is an identifiable cardioembolic source which is the case in about 30% of ischemic stroke, a higher proportion in recent studies using transoesophageal echocardiography. It is not clear that transoesophageal echocardiography provides much more information for clinical decision-making than transthoracic echocardiography, although it certainly provides more anatomical information in selected patients. This article summarises the diagnostic armamentarium which is used for the diagnosis of stroke and gives an overview of clinically reliable and relevant measures.
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