Of mouse and man--what is the value of the mouse in predicting gene expression in humans?
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Updated: Sep 27, 2026
09:35
A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Published on: August 16, 2017
Drug Discovery Today
|March 8, 2003
Abstract:
The mouse is the most commonly used mammalian species in biomedical research and is widely regarded as a human surrogate species. In this Editorial, Robert Coleman discusses the validity of this assumption and cautions against the unquestioning acceptance of the mouse an experimental model for drug discovery and development.
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