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Haemorheological changes during the menstrual cycle.

D V B Dapper1, B C Didia

  • 1Department of Human Physiology, College of Health Sciences, University of Port Harcourt, P.M.B. 5323, Port Harcourt, Nigeria.

East African Medical Journal
|March 11, 2003
PubMed
Summary

Haematocrit (Hct), Whole Blood Relative Viscosity (WBRV), Erythrocyte Sedimentation Rate (ESR), and Fibrinogen Concentration (FC) significantly change throughout the menstrual cycle. These haemorheological parameters exhibit distinct patterns across different cycle phases, indicating physiological variations.

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Area of Science:

  • Physiology
  • Haematology
  • Reproductive Health

Background:

  • The menstrual cycle involves complex physiological changes.
  • Haemorheological parameters, crucial for blood flow, may fluctuate during the cycle.

Purpose of the Study:

  • To investigate variations in haematocrit (Hct), Whole Blood Relative Viscosity (WBRV), Erythrocyte Sedimentation Rate (ESR), and Fibrinogen Concentration (FC) across the menstrual cycle.

Main Methods:

  • A cross-sectional prospective study involving 350 female undergraduate students.
  • Data collected from the University of Port Harcourt, Nigeria.
  • Assessed four key haemorheological parameters.

Main Results:

  • Significant variations (p<0.05) were observed in all assessed parameters across menstrual cycle phases.

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  • Hct and WBRV were highest during ovulation, lowest during menstruation.
  • ESR was highest during menstruation, lowest during ovulation.
  • FC was highest during menstruation, lowest during the follicular phase.

    • Conclusions:

    • The study confirms significant variations in key haemorheological parameters during the normal menstrual cycle.
    • These findings highlight the dynamic nature of blood properties throughout the reproductive cycle.