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Using treatment algorithms to bring patients to remission
1St. Paul Hospital, University of Texas Southwest Medical School, Dallas 75235-9101, USA. madhukar.trivedi@utsouthwestern.edu
The Journal of Clinical Psychiatry
|March 11, 2003
Summary
Many patients do not achieve full remission with antidepressants. Sequential treatment strategies, including switching or augmenting antidepressants, can help manage residual symptoms and improve outcomes.
Area of Science:
- Psychiatry
- Pharmacology
- Clinical Medicine
Background:
- Many patients treated with antidepressants do not achieve full remission.
- Residual symptoms and partial response to antidepressants incur significant social and economic costs.
Purpose of the Study:
- To review sequential treatment approaches for patients with incomplete remission to antidepressant therapy.
- To highlight the role of treatment guidelines and algorithms in guiding therapeutic decisions.
Main Methods:
- Literature review of current antidepressant treatment alternatives.
- Analysis of the utility of clinical guidelines and decision-support algorithms.
Main Results:
- The number of treatment alternatives for antidepressant non-remission has increased.
- Treatment guidelines and algorithms offer structured support for clinicians.
- These tools enhance clinician autonomy in treatment selection and assessment.
Conclusions:
- Sequential treatment strategies are crucial for patients with incomplete antidepressant response.
- Algorithms and guidelines aid clinicians in navigating complex treatment decisions.
- Effective use of these tools supports personalized patient care and optimizes treatment outcomes.