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[Effect of redox-modified fibrinogen on blood leukocyte functions]
1Research Institute of Physicochemical Medicine, Ministry of Health of Russian Federation, Malaya Pirogovskaya ul. 1A, Moscow, 119992 Russia.
Biofizika
|March 13, 2003
Abstract:
The influence of oxidized fibrinogen on the intensity of luminol-dependent chemilumin escence of blood leukocytes, stimulated by opsonized zymosan was studied. It was shown that the introduction of fibrinogen modified by UV-irradiation in to a suspension of cells resulted in a significant increase in the intensity of the luminol-dependent chemiluminescence of leukocytes. It was suggested that oxidized fibrinogen can influence blood leukocytes, enhancing their functional activity.