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Updated: Sep 27, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Occult supraglottic lymphatic malformation presenting as obstructive sleep apnea
James Chan1, Abbas Younes, Peter J Koltai
1Department of Otolaryngology and Communicative Disorders, The Cleveland Clinic Foundation, A71, 9500 Euclid Avenue, Cleveland, OH 44195, USA. chanj@ccf.org
Insights
Pediatric obstructive sleep apnea can stem from rare supraglottic lymphatic malformations. Early diagnosis via laryngeal exam is crucial for effective management, avoiding tracheotomy.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Medical Genetics
Background:
- Sleep disordered breathing and obstructive sleep apnea (OSA) are prevalent in children, often linked to adenotonsillar hypertrophy.
- Oropharyngeal obstruction is the typical cause of pediatric OSA.
Observation:
- A case study of a child presenting with adenoidal hypertrophy and OSA.
- An unusual finding of an occult supraglottic lymphatic malformation (LM) was identified as the underlying cause.
- The diagnosis was established through fiberoptic laryngeal examination.
Findings:
- Occult supraglottic LMs are a rare etiology of pediatric OSA.
- These malformations can be challenging to diagnose and manage due to airway compromise.
- Successful management involved endoscopy and carbon-dioxide laser treatment, avoiding tracheotomy.
Implications:
- Highlights the importance of thorough laryngeal examination in diagnosing pediatric OSA.
- Suggests minimally invasive techniques for managing supraglottic LMs.
- Emphasizes the potential for recurrence and the need for vigilant follow-up.
Abstract:
Sleep disordered breathing and obstructive sleep apnea is commonly encountered in the pediatric population. In many cases, it is the result of oropharyngeal obstruction secondary to adenoidal or adenotonsillar hypertrophy. We describe an unusual case of a child with adenoidal hypertrophy who had an occult supraglottic lymphatic malformation that manifested as obstructive sleep apnea. The management of this lesion is discussed including the use of endoscopy, carbon-dioxide laser, and the decision to avoid a tracheotomy. Occult supraglottic lymphatic malformations (LMs) are a rare cause of obstructive sleep apnea, the diagnosis of which will be missed without fiberoptic laryngeal examination. They are challenging to manage because of the airway involvement and propensity to recur.
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