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The NIT domain: a predicted nitrate-responsive module in bacterial sensory receptors
Chengyi J Shu1, Luke E Ulrich, Igor B Zhulin
1School of Biology, Georgia Institute of Technology, Atlanta, GA 30332-0230, USA.
Trends in Biochemical Sciences
|March 14, 2003
Abstract:
A nitrate- and nitrite-sensing (NIT) domain as found in the NasR protein, has been detected in various receptor components of signal transduction pathways in different bacterial lineages. Cellular functions controlled by receptors that contain this novel domain include regulation of gene expression (transcription anti-terminators and histidine kinases), cell motility (chemotaxis receptors) and enzyme activity (diguanylate cyclases and phosphodiesterases).