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Published on: February 12, 2018
Intraocular hemorrhage after systemic thrombolytic therapy in a patient with exudative macular degeneration
A R Djalilian1, H C Cantrill, T W Samuelson
1Department of Ophthalmology, Regions Hospital, St. Paul, Minnesota, USA. djaliliana@nei.nih.gov
Purpose:
To report a hemorrhagic complication from thrombolytic therapy in a patient with exudative macular degeneration.
Case Report:
A 75 year old patient with exudative macular degeneration developed pain and loss of vision in the left eye shortly after receiving tissue plasminogen activator (t-PA) for a myocardial infarction. Examination revealed the patient to be in angle closure. A CT scan revealed the etiology of the angle closure to be a dense vitreous hemorrhage pushing the iris-lens diaphragm forward. Intraocular pressure was treated successfully, but the final visual acuity was only light perception.
Conclusions:
Thrombolytic therapy can lead to devastating intraocular hemorrhages. The presence of exudative macular degeneration may potentially increase the risk of developing such complications.
