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Published on: January 7, 2014
Clear cell meningioma: case report and literature review
Kayhan Kuzeyli1, Ertuğrul Cakir, Haydar Usul
1Department of Neurosurgery, Karadeni;z Technical University, School of Medicine, 61080 Trabzon, Turkey. ertugrulcakir@hotmail.com
Abstract:
The clear cell meningioma is rare and a recently described histologic variant of meningioma. The most interesting aspect of clear cell meningioma is the high recurrence rate and agressiveness. Until now 17 intracranial clear cell meningioma cases had been reported in the English language literature. We present 2 new cases of clear cell meningioma which is discussed with the relevant literature.
Insights
Clear cell meningioma, a rare brain tumor variant, exhibits high recurrence rates and aggressive behavior. This report details two new cases, adding to the limited literature on this challenging tumor type.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Clear cell meningioma is a rare histologic variant.
- This tumor type is recently described in medical literature.
- Limited data exists on clear cell meningioma, with only 17 prior reported intracranial cases.
Observation:
- Two new cases of intracranial clear cell meningioma are presented.
- These cases highlight the tumor's distinct histologic features.
- Clinical presentation and management of these cases are discussed.
Findings:
- Clear cell meningioma demonstrates a high rate of recurrence.
- The tumor is characterized by aggressive behavior.
- This histological variant requires careful monitoring and management.
Implications:
- Increased awareness of clear cell meningioma is crucial for timely diagnosis.
- Understanding its aggressive nature aids in treatment planning.
- Further research is needed to improve outcomes for patients with this rare tumor.

