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[Ischemic left ventricular diastolic dysfunction at females: clinical aspect]
1Facultatea de Medicină Clinica a VI-a Medicală, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Summary
Ischemic heart dysfunction in women occurs later in life and is characterized by ischemic cardiomyopathy and angina. Despite similar systolic function, women experience more diastolic dysfunction, left ventricular hypertrophy, and cardiac decompensation.
Area of Science:
- Cardiology
- Internal Medicine
- Women's Health
Context:
- Coronary heart disease (CHD) prevalence in women approaches that of men at older ages.
- Studies assessing ischemic cardiac dysfunction often underrepresent women.
- Understanding the clinical profile of women with ischemic heart dysfunction is crucial.
Purpose:
- To analyze the clinical profile of women diagnosed with ischemic heart dysfunction.
- To compare the characteristics of ischemic heart dysfunction between female and male patients.
Summary:
- This study analyzed 189 patients (63 females, 126 males) with coronary heart disease, examining prevalence, risk factors, symptoms, and diagnostic findings.
- Women with ischemic heart dysfunction were older, more frequently diagnosed with ischemic cardiomyopathy, and experienced higher rates of cardiac decompensation and arterial hypertension.
- While systolic function was similar, women showed higher prevalence of left ventricular hypertrophy and diastolic dysfunction, with elevated cholesterol and LDL levels.
Impact:
- Highlights significant differences in the clinical presentation and progression of ischemic heart dysfunction between genders.
- Emphasizes the need for tailored diagnostic and treatment strategies for women with ischemic heart conditions.
- Contributes to a better understanding of cardiovascular disease in aging women.