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Related Experiment Videos

Alcohol and psychiatric comorbidity.

Jack R Cornelius1, Oscar Bukstein, Ihsan Salloum

  • 1Pittsburgh Adolescent Alcohol Research Center, Center for Education and Drug Abuse Research, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

Recent Developments in Alcoholism : an Official Publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism
|March 18, 2003
PubMed
Summary

Comorbid psychiatric disorders and drug use disorders (DUDs) are common in alcoholism and predict relapse. Empirically proven treatments are lacking for most dual diagnosis patients, highlighting a critical gap in care.

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Area of Science:

  • Psychiatry and Addiction Medicine

Background:

  • Comorbid psychiatric disorders and drug use disorders (DUDs) are highly prevalent in individuals with alcoholism.
  • These co-occurring conditions are associated with an increased risk and shorter time to relapse of alcoholism.
  • Existing research and treatment studies for dual diagnosis populations are limited, particularly for conditions beyond major depression and anxiety disorders.

Purpose of the Study:

  • To highlight the significant gap in evidence-based treatment options for alcoholics with comorbid psychiatric and drug use disorders.
  • To underscore the need for controlled treatment studies addressing the broad spectrum of dual diagnosis in alcoholism.

Main Methods:

  • Review of existing literature on comorbid disorders in alcoholism.
  • Analysis of controlled treatment studies focusing on dual diagnosis populations.

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  • Identification of treatment efficacy for specific comorbidities like major depression and anxiety disorders.

    • Main Results:

    • While some treatments show efficacy for comorbid major depression (SSRIs, tricyclic antidepressants) and anxiety disorders (buspirone) in alcoholics, these studies are limited.
    • Controlled treatment studies for alcoholics with other comorbid disorders are notably absent.
    • There is a lack of empirically proven treatments for the majority of dual diagnosis cases in alcoholism.

    Conclusions:

    • A significant treatment gap exists for alcoholics with comorbid psychiatric and drug use disorders beyond major depression and anxiety.
    • Further controlled research is urgently needed to develop and validate effective treatments for these complex dual diagnosis populations.
    • Addressing this gap is crucial for improving relapse prevention and overall outcomes for individuals with alcoholism and co-occurring conditions.