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Updated: Jul 30, 2026

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
Antifeedant activity of some pentacyclic triterpene acids and their fatty acid ester analogues
Uppuluri V Mallavadhani1, Anita Mahapatra, S Sabitha Raja
1Forest and Marine Products Department, Natural Resources Division, Regional Research Laboratory (CSIR), Bhubaneswar-751 013, Orissa, India. uvmavadani@yahoo.com
Abstract:
The 3-O-fatty acid ester derivatives (C(12)-C(18)) of two pentacyclic triterpenic acids, ursolic acid and oleanolic acid, were synthesized under mild esterification conditions in excellent yields (80-85%) and screened for their antifeedant activity, together with the parent acids, against the agricultural pest tobacco caterpillar larvae (Spodoptera litura F) in a no-choice laboratory study. The Urs-12-ene-28-carboxy-3beta-octadecanoate and olean-12-ene-28-carboxy-3beta-hexadecanoate were found to exhibit exceptionally potent antifeedant activities at 50 microg/cm(2) concentration, even after 48 h.
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