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Vomeronasal organ: pheromone recognition with a twist
Natasha Thorne1, Hubert Amrein
1Department of Molecular Genetics and Microbiology, Duke University Medical Center, 252 CARL Bldg./Research Drive, Durham, NC 27710, USA. hoa1@duke.edu
Current Biology : CB
|March 21, 2003
Abstract:
Pheromones are detected by the vomeronasal organ using members of two receptor superfamilies: the V1Rs and V2Rs. New studies show that MHC class I molecules are co-expressed in particular combinations with specific V2Rs in the vomeronasal organ. The role of these MHC molecules is unknown, but they may be of considerable biological significance.