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Related Experiment Videos

Using a saline chaser to decrease contrast media in abdominal CT.

Paul J Dorio1, Fred T Lee, Kevin P Henseler

  • 1Department of Radiology, University of Wisconsin Hospital & Clinics, 600 Highland Ave., Madison, WI 53792-3252, USA.

AJR. American Journal of Roentgenology
|March 21, 2003
PubMed
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Using 100 mL of contrast material with a saline chaser for abdominal CT did not significantly impact liver lesion conspicuity compared to 150 mL alone. This approach may offer cost savings and reduce risks associated with contrast agents.

Area of Science:

  • Radiology
  • Medical Imaging
  • Diagnostic Procedures

Background:

  • Contrast-enhanced computed tomography (CT) is crucial for detecting hepatic tumors.
  • Optimizing contrast material volume is essential for diagnostic accuracy and patient safety.

Purpose of the Study:

  • To compare the conspicuity of hepatic tumors on CT scans using two different volumes of iodinated contrast material.
  • To evaluate the impact of a saline chaser on image quality and lesion detection.

Main Methods:

  • A randomized study involving 26 patients with 86 hypoattenuating liver metastases.
  • Patients underwent two CT sessions: one with 150 mL contrast material, and another with 100 mL contrast material followed by a 50 mL saline chaser.
  • Attenuation values of liver parenchyma, metastases, and organs were measured.

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Main Results:

  • A slight, but not clinically significant, difference in liver and tumor attenuation was observed between the two protocols.
  • Hepatic tumor conspicuity showed a marginal increase with 150 mL of contrast material compared to the 100 mL plus chaser group.
  • Enhancement of kidney, spleen, and vascular structures was greater with the higher contrast volume.

Conclusions:

  • Administering 100 mL of contrast material with a saline chaser is a viable alternative to 150 mL alone for abdominal CT.
  • This reduced volume protocol does not meaningfully compromise liver parenchyma attenuation or lesion conspicuity.
  • Routine use of a saline chaser may lead to cost savings and a lower risk of contrast-induced nephropathy.