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Updated: Sep 26, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
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Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

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Multidetector CT angiography of the aortoiliac system and lower extremities: a prospective comparison with digital

Michael L Martin1, Kiang H Tay, Borys Flak

  • 1Department of Radiology, University of British Columbia, UBC Hospital Site, 2211 Wesbrook Mall, Vancouver, B. C., V6T 2B5, Canada.

AJR. American Journal of Roentgenology
|March 21, 2003
PubMed

Insights

Multidetector CT (MDCT) angiography accurately detects lower extremity arterial disease, showing similar reliability to digital subtraction angiography (DSA). MDCT angiography visualizes more vascular segments, especially in the calves, aiding in diagnosing atheroocclusive disease.

Area of Science:

  • Vascular Imaging
  • Radiology
  • Cardiovascular Disease

Background:

  • Atheroocclusive disease significantly impacts lower extremity circulation.
  • Accurate imaging is crucial for diagnosing and managing peripheral artery disease.
  • Digital subtraction angiography (DSA) is a traditional standard for evaluating aortoiliac and lower extremity arteries.

Purpose of the Study:

  • To assess the accuracy and reliability of multidetector CT (MDCT) angiography.
  • To compare MDCT angiography with digital subtraction angiography (DSA) for detecting atheroocclusive disease.
  • To evaluate MDCT angiography's effectiveness in visualizing the aortoiliac system and lower extremities.

Main Methods:

  • Forty-one patients with ischemic legs underwent both MDCT angiography and DSA.
  • Arterial segments were analyzed for stenosis and occlusion by three independent observers.
  • Sensitivity, specificity, and intertechnique/interobserver agreement were calculated using kappa statistics.

Main Results:

  • MDCT angiography demonstrated high sensitivity (88.6%) and specificity (97.7%) for detecting stenoses/occlusions of at least 75%.
  • Substantial agreement was found between MDCT angiography and DSA (kappa > 0.4) in 97.1% of segments.
  • MDCT angiography visualized more patent vascular segments (1192 vs 1091), particularly in calf vessels.

Conclusions:

  • MDCT angiography is an accurate and reliable tool for diagnosing atheroocclusive disease in the aortoiliac system and lower extremities.
  • Its reliability is comparable to that of DSA.
  • MDCT angiography offers superior visualization of vascular segments, especially distal vessels in the calves.
Abstract

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