Related Experiment Video
Updated: Aug 18, 2026

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations
Published on: August 7, 2018
Treatment of lumbar disks with chymopapain
Abstract:
Symptoms arising from a herniated disk appear when the nucleus pulposus or soft inner portion of the disk bulges against a nerve root. When conservative treatment fails to help the patient, the enzyme chymopapain is currently being used in the treatment of such conditions. Injected directly into the disk, the chymopapain dissolves the nucleus by enzymatic action which selectively breaks certain bonds within the nucleus. The pressure within the center is decreased, hence the pressure against the nerve root is relieved, alleviating the symptoms. Because back care is particularly important following such treatment, physical therapy is valuable in promoting continued relief. The major emphasis of the therapy back care program is on abdominal strengthening exercises and postural training.
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