Post prandial changes in colonic motility related to serum gastrin levels

Colonic motor activity and serum gastrin levels were correlated during a basal period and after a meal in 16 subjects. Motor activity preceded the gastrin response. The motility index and the serum gastrin levels rose in parallel, but the motility fell before later showing a second rise. The frequency response showed the earliest change and since it preceded the gastrin rise may be neurogenic. This response was later "extinguished" and replaced by one of waves of increasing amplitude; the sustained nature of this response fitted more closely the gastrin response.