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Major histocompatibility complex heterozygote superiority during coinfection

Erin E McClelland1, Dustin J Penn, Wayne K Potts

  • 1Biology Department, University of Utah, Salt Lake City, UT 84112, USA.

Infection and Immunity
|March 26, 2003
PubMed
Summary

Major histocompatibility complex (MHC) heterozygote superiority was observed in mice with multiple infections. This finding explains how disease-susceptibility alleles persist in populations, contributing to MHC diversity.

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