Role of membrane microdomain rafts in TNFR-mediated signal transduction

Interferon decreases VEGF levels in patients with chronic myeloid leukemia treated with imatinib.

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Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferation.

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Reversible activation of c-Myc in thymocytes enhances positive selection and induces proliferation and apoptosis in vitro.

Oncogene·2000

A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts.

The Journal of biological chemistry·2000

CD95: more than just a death factor?

Nature cell biology·2000

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release.

Genes & development·1999

NLRX1 is a critical neutrophil checkpoint modulating ferroptosis and suppressing NETosis to attenuate joint damage in arthritis.

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Ubiquitination-mediated degradation of NLRX1 drives metabolic vulnerability and accelerates intervertebral disc degeneration.

Cell death and differentiation·2026

VMP1 restricts STING trafficking and activation through controlling CDIPT recruitment to ER membrane curvature.

Cell death and differentiation·2026

Convergent TBK1 loss of function drives gasdermin E dependent pyroptosis and motor neuron degeneration across ALS genotypes.

Cell death and differentiation·2026

ADORA1 inhibition suppresses colon cancer development via hippo tumor suppressor pathway.

Cell death and differentiation·2026

PGC1α-mediated upregulation of PHD2 represses HIF-signaling, limiting prostate cancer progression.

Cell death and differentiation·2026

Curved by Design: Applying Microfluidic Principles for Nonplanar and Planar Suspended Tissue Patterning to the Development of Bladder Models with Tunable Mechanics.

bioRxiv : the preprint server for biology·2026

Ultrastructural and Proteomic Signatures of Mechanoadaptive Fibroblast Remodeling across Microphysiological and Mesoscale Shear Platforms.

bioRxiv : the preprint server for biology·2026

Two slits good, four slits bad? Assessing the hemodynamic impact of modifications to microvascular plugs in pulmonary flow restriction using a bench-top model.

Cardiology in the young·2026

Flecainide- and isoproterenol-induced alterations in heart rate variability and DFA-derived physiological complexity in anesthetized mice.

BMC cardiovascular disorders·2026

Self-organized optofluidic locking enables stable single-frequency lasing in dynamic liquid media.

Science advances·2026

Extracellular vesicles redefine immune modulation through Toll-like receptor networks.

Expert opinion on therapeutic targets·2026

Related Experiment Videos

Role of membrane microdomain rafts in TNFR-mediated signal transduction

Related Concept Videos

Interferon decreases VEGF levels in patients with chronic myeloid leukemia treated with imatinib.

Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferation.

Reversible activation of c-Myc in thymocytes enhances positive selection and induces proliferation and apoptosis in vitro.

A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts.

CD95: more than just a death factor?

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release.

NLRX1 is a critical neutrophil checkpoint modulating ferroptosis and suppressing NETosis to attenuate joint damage in arthritis.

Ubiquitination-mediated degradation of NLRX1 drives metabolic vulnerability and accelerates intervertebral disc degeneration.

VMP1 restricts STING trafficking and activation through controlling CDIPT recruitment to ER membrane curvature.

Convergent TBK1 loss of function drives gasdermin E dependent pyroptosis and motor neuron degeneration across ALS genotypes.

ADORA1 inhibition suppresses colon cancer development via hippo tumor suppressor pathway.

PGC1α-mediated upregulation of PHD2 represses HIF-signaling, limiting prostate cancer progression.

Curved by Design: Applying Microfluidic Principles for Nonplanar and Planar Suspended Tissue Patterning to the Development of Bladder Models with Tunable Mechanics.

Ultrastructural and Proteomic Signatures of Mechanoadaptive Fibroblast Remodeling across Microphysiological and Mesoscale Shear Platforms.

Two slits good, four slits bad? Assessing the hemodynamic impact of modifications to microvascular plugs in pulmonary flow restriction using a bench-top model.

Flecainide- and isoproterenol-induced alterations in heart rate variability and DFA-derived physiological complexity in anesthetized mice.

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Role of membrane microdomain rafts in TNFR-mediated signal transduction

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