Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Complement components and their autoantibodies.

P Norsworthy1, K A Davies

  • 1Rhuematology Section, Imperial College of Science, Technology and Medicine, London.

Molecular Biotechnology
|April 1, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating the effectiveness of commercially available mouthwash on SARS-CoV-2 in vivo using viable virus titre as the primary outcome. A randomised controlled trial.

Access microbiology·2024
Same author

European survey on the current surveillance practices, management guidelines, treatment pathways and heterogeneity of testing of Clostridioides difficile, 2018-2019: results from The Combatting Bacterial Resistance in Europe CDI (COMBACTE-CDI).

The Journal of hospital infection·2022
Same author

Do probiotics prevent antibiotic-associated diarrhoea? Results of a multicentre randomized placebo-controlled trial.

The Journal of hospital infection·2020
Same author

Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series.

Molecular psychiatry·2018
Same author

Is there a relationship between the presence of the binary toxin genes in Clostridium difficile strains and the severity of C. difficile infection (CDI)?

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2017
Same author

Phylogenetics of Australasian gall flies (Diptera: Fergusoninidae): Evolutionary patterns of host-shifting and gall morphology.

Molecular phylogenetics and evolution·2017
Same journal

Cloning and Functional Characterization of AhyAP-T65Lig, an ATP-Dependent DNA Ligase from Trabzonvirus AP-T65.

Molecular biotechnology·2026
Same journal

Overexpression of the ATP-Citrate Lyase Gene Enhances Ganoderic Acid Biosynthesis in Ganoderma lingzhi.

Molecular biotechnology·2026
Same journal

CRISPR/Cas9 Mediated Genome Editing for Enhancing Abiotic Stress Tolerance in Rice: An Omics Guided Perspective.

Molecular biotechnology·2026
Same journal

Functionalization of Chitosan with Silver Oxide and Berberis aristata for Bioactive Composites with In Vivo Wound Healing Evaluation.

Molecular biotechnology·2026
Same journal

Resilience in Tribolium Castaneum Through Antioxidant Priming Under Phosphine-Induced Oxidative Stress.

Molecular biotechnology·2026
Same journal

MicroRNA-181a-5p promotes papillary thyroid carcinoma progress via the PTEN/AKT pathway.

Molecular biotechnology·2026
See all related articles

This study focuses on autoantibodies targeting complement components, which are key players in the immune system. Understanding these autoantibodies is crucial for diagnosing and treating autoimmune diseases.

Area of Science:

  • Immunology
  • Autoimmunity
  • Complement System

Background:

  • The immune system protects against pathogens.
  • Autoimmune diseases arise from immune responses against self-antigens, causing tissue damage.
  • Autoimmunity is defined as a disease-causing immune response to self-antigens.

Purpose of the Study:

  • To explore autoantibodies targeting components of the complement system.
  • To provide a comprehensive overview of autoantibodies against complement factors.

Main Methods:

  • Literature review and synthesis of existing research.
  • Analysis of immunological mechanisms involved in autoimmunity.
  • Focus on autoantibodies specific to complement proteins.

Related Experiment Videos

Main Results:

  • Autoantibodies against complement components are significant in autoimmune diseases.
  • These autoantibodies can activate or inhibit complement pathways, leading to pathology.
  • Specific complement targets and associated diseases are identified.

Conclusions:

  • Autoantibodies to complement components represent a critical aspect of autoimmunity.
  • Further research into these autoantibodies can lead to improved diagnostics and therapeutics.
  • Understanding the role of complement autoantibodies is vital for managing autoimmune conditions.