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Updated: Sep 26, 2026

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
Published on: May 19, 2018
[Morphological differences between follicular lymphomas and follicular hyperplasia of the lymph nodes]
Iu A Krivolapov1, V L Belianin
1Saint-Petersburg Medical Academy of Postgraduate Training, 193015, Saint-Petersburg.
Abstract:
A study was performed in 80 patients with follicular lymphomas and 61 patients with follicular hyperplasia of lymph nodes. The sensitivity, specificity, prognostic value, and the positive and negative likelihood ratio of various histological differentially diagnostic parameters were estimated. The signs that are of great informative value were as follows: the presence (or absence) of concentric layers of mantle cells, follicular polarization, the presence of histiocytes with phagocytosed nuclear debris in the follicles and atypical follicular cells outside the follicles.
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