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Related Experiment Videos

Nocturia and benign prostatic hyperplasia.

Koji Yoshimura1, Hiroki Ohara, Kentaro Ichioka

  • 1Department of Urology, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.

Urology
|April 3, 2003
PubMed
Summary

Nocturia, or nighttime urination, affects over 70% of men with symptomatic benign prostatic hyperplasia (BPH). Treatments for BPH offer limited improvement for nocturia symptoms.

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Area of Science:

  • Urology
  • Men's Health
  • Lower Urinary Tract Symptoms

Background:

  • Nocturia is a common and bothersome lower urinary tract symptom.
  • Benign prostatic hyperplasia (BPH) is a prevalent condition in aging men, often associated with nocturia.
  • Understanding nocturia's prevalence and treatment outcomes in BPH is crucial for patient management.

Purpose of the Study:

  • To determine the frequency and risk factors of nocturia in patients diagnosed with symptomatic BPH.
  • To evaluate the effectiveness of BPH treatments on improving nocturia symptoms.

Main Methods:

  • A cohort of 505 newly diagnosed symptomatic BPH patients were assessed for nocturia prevalence and risk factors.
  • International Prostate Symptom Score (IPSS) and other clinical parameters (age, prostate volume, PSA, uroflow) were analyzed.

Related Experiment Videos

  • Treatment outcomes were evaluated in 165 patients on tamsulosin and 138 patients undergoing transurethral resection of the prostate (TURP).

    • Main Results:

    • Nocturia (waking ≥2 times/night) was reported by 71.1% of the BPH patients.
    • Patient age, urgency score, and functional bladder capacity were significantly associated with nocturia.
    • Tamsulosin and TURP improved nocturia in 17.9% and 32.2% of patients, respectively, with the lowest improvement rates among all IPSS symptoms.

    Conclusions:

    • Nocturia is highly prevalent in symptomatic BPH patients, exceeding rates found in community studies.
    • While BPH treatments can reduce nocturia episodes, the improvement is modest compared to other BPH symptoms.
    • Further research may be needed to optimize nocturia management in BPH patients.