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Incidental control of rosacea by somatostatin
Claudine Piérard-Franchimont1, Pascale Quatresooz, Gérald E Piérard
1Department of Dermatopathology, University Medical Center of Liège, Belgium.
Background:
The precise pathomechanism of rosacea remains elusive. The disease commonly requires long-term treatments using topical or oral therapies.
Objective:
This report presents incidental findings about the possible modulatory role of somatostatin in the outcome of rosacea.
Method:
Four patients presenting long-standing recalcitrant facial rosacea were treated with octreotide for diabetic retinopathy.
Results:
Rosacea improved rapidly and even cleared without any recurrence in 3 of the patients.
Conclusion:
The beneficial effect might be attributed to inhibitory actions on the sebaceous gland, the neovascularization and/or on the inflammatory process.