Related Experiment Video
Updated: Aug 3, 2026
10:52
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Visceral larva migrans mimicking lymphoma
Claude Bachmeyer1, Gérard Lamarque, Rodica Morariu
1Département de Médecine Interne, Center Hospitalier Laënnec, Creil, France. claude.bachmeyer@ch-creil.fr
Chest
|April 10, 2003
Summary
Visceral larva migrans can present with symptoms mimicking lymphoma in adults. Early diagnosis through serology and prompt treatment with albendazole led to significant patient improvement.
Area of Science:
- Parasitology
- Infectious Diseases
- Clinical Medicine
Background:
- Visceral larva migrans (VLM) is a human parasitic infection caused by the larval stage of nematodes, primarily Toxocara species.
- VLM is typically diagnosed in children, but adult cases can occur, presenting with diverse and sometimes misleading clinical manifestations.
Observation:
- A case of VLM in an adult is presented, characterized by fever, night sweats, weight loss, hilar and mediastinal lymphadenopathy, bilateral pleural effusion, and eosinophilia.
- These clinical and radiological findings initially mimicked lymphoma, highlighting a diagnostic challenge.
Findings:
- Malignancy was ruled out through comprehensive investigations.
- Diagnosis of VLM was confirmed by a positive serologic test for Toxocara canis.
Implications:
- This case underscores the importance of considering VLM in the differential diagnosis of unexplained systemic symptoms and lymphadenopathy in adults.
- Prompt diagnosis and treatment with antiparasitic agents like albendazole are crucial for favorable outcomes in VLM.
- Further research into the varied presentations of VLM in adults may improve early recognition and management strategies.
