Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new, liquid-based cytology technique.

Birgit Weynand1, Martine Berlière, Esther Haumont

  • 1Departments of Pathology, Gynecology and Obstetrics, Université Catholique de Louvain, Cliniques universitaires St Luc, Brussels, Belgium.

Acta Cytologica
|April 11, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Transcriptomic Atlas of Chronic Lung Allograft Dysfunction.

The European respiratory journal·2026
Same author

The critical role of accurate neoplastic cell percentage (NCP) assessment: investigating targeted training strategies for pulmonary biopsy and cytology specimens.

Virchows Archiv : an international journal of pathology·2026
Same author

The role of external quality assessment in detecting immunohistochemical analyses with inferior performance: focus on the anti-ER SP1 clone.

Virchows Archiv : an international journal of pathology·2026
Same author

Masquerading as an Interstitial Lung Disease: Intravascular Large B-Cell Lymphoma With Prominent Neo-Angiogenesis.

International journal of surgical pathology·2026
Same author

Cellularity of Routinely Prepared Cell Blocks: Insights From an International Study.

Cytopathology : official journal of the British Society for Clinical Cytology·2026
Same author

A detailed protocol for open and low-cost six-plex immunofluorescence (Flex-6 mIHF) with a proof-of-concept study on breast cancer tissue.

Journal of microscopy·2026

The Papspin liquid-based cytology technique demonstrated comparable detection rates for cervical cell abnormalities to the traditional Pap smear. Papspin also showed improved specimen quality and easier diagnosis of fungal infections.

Area of Science:

  • Cytopathology
  • Gynecologic Oncology

Background:

  • Cervical cancer screening relies on accurate cytologic evaluation.
  • Liquid-based cytology aims to improve sample quality and diagnostic yield compared to conventional Pap smears.

Purpose of the Study:

  • To evaluate the performance of the new Papspin liquid-based cytology technique.
  • To compare Papspin with the conventional Pap smear method for cervical sample analysis.

Main Methods:

  • Three thousand cervical samples were analyzed using both Papspin and conventional Pap smear techniques.
  • Samples were collected using a Cervex Brush, with one cytospin prepared per vial for Papspin.

Main Results:

  • An identical rate of epithelial cell abnormalities (3.8%) was detected by both methods.

Related Experiment Videos

  • Diagnostic concordance was 86%, with minor differences in fungal infections and non-neoplastic categories.
  • Papspin showed fewer unsatisfactory specimens (Satisfactory But Limited By - SBLB) due to better preservation of endocervical cells.

    • Conclusions:

    • Papspin is a viable alternative to conventional Pap smears, offering comparable detection of abnormalities.
    • The technique enhances specimen quality, particularly for SBLB cases, and facilitates fungal infection diagnosis.
    • Papspin shows potential for improved HPV testing integration.