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Updated: Mar 24, 2026

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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Masquerading as an Interstitial Lung Disease: Intravascular Large B-Cell Lymphoma With Prominent Neo-Angiogenesis
Andreas Lancelot1, Anne-Marie Delsupehe2, Vibeke K J Vergote3,4
1Department of Pathology, University Hospitals Leuven, Leuven, Belgium.
International Journal of Surgical Pathology
|March 23, 2026
Summary
Intravascular large B-cell lymphoma (ILBCL) can mimic other diseases. This rare cancer, characterized by B cells in blood vessels, presented with lung symptoms mimicking hypersensitivity pneumonitis.
Area of Science:
- Hematology
- Pulmonary Medicine
- Oncology
Background:
- Intravascular large B-cell lymphoma (ILBCL) is a rare hematologic malignancy.
- ILBCL is characterized by neoplastic B cells confined to the intravascular space.
- Clinical presentation varies based on affected organs, often mimicking other conditions.
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