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Incidental Detection of Diffuse Large B-cell Lymphoma by Non-invasive Prenatal Testing: A Case Report
Martin Vanderdonck1, Patrizia Chiarappa1, Armelle Duquenne1
1Human Genetics, Cliniques universitaires Saint-Luc, Brussels, BEL.
Cureus
|June 18, 2026
Summary
Non-invasive prenatal testing (NIPT) can incidentally detect maternal cancer DNA. This case highlights NIPT
Area of Science:
- Genetics
- Oncology
- Maternal-Fetal Medicine
Background:
- Non-invasive prenatal testing (NIPT) analyzes cell-free DNA (cfDNA) in maternal plasma for fetal aneuploidies.
- cfDNA originates from both placental and maternal sources, including potential tumor DNA.
