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Updated: Aug 14, 2026

Methods for Acute and Subacute Murine Hindlimb Ischemia
Published on: June 21, 2016
[Metabolic changes caused by artificial ischemia in knee arthroscopy]
1I. chirurgická klinika 1. lékarské fakulty Univerzity Karlovy, U nemocnice 2, 120 00 Praha 2, Czech Republic.
Abstract:
The most important complication of arthroscopy of the knee is DVT. We studied 53 patients who undergoing arthroscopy with artificial ischemia of lower limb. We examined some biochemics and haematological dates, for example lactate, APTT, INR, PAI-1 etc. In our collection we did not find any case of thromboembolic disease. It seems, that arthroscopy operation with artificial ischemia of lower limb do not increase the risks of DVT. We means, that especially in cases with longer tourniquet time (more than 30 min) is better, when we give some type of Heparin (best is LMWH) as prevention of DVT, because in laboratory results we found significant increase of PAI-1. It is possible, that it can be caused by the rising thrombus.
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