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Critical care of the obese and bariatric surgical patient
Daniela Levi1, Elliot R Goodman, Mayank Patel
1Albert Einstein College of Medicine, Critical Care Services, Montefiore Medical Center, 111 East 210 Street, Bronx, NY 10467, USA. dlevi@montefiore.org
Abstract:
Obesity is associated with a chronic inflammatory state that predisposes to atherogenesis, thrombogenesis, and carcinogenesis and may increase susceptibility to infections. Critically ill, obese patients have higher mortality. MOF is the best predictor of ICU mortality for obese patients. Pulmonary hypertension and higher BMI are associated with higher surgical risk. Progress in surgical technique and anesthesia has substantially improved the safety of performing operations in severely obese patients.
Insights
Obesity causes chronic inflammation, increasing risks for critical illness and surgical complications. However, advancements in surgical techniques enhance safety for obese patients undergoing operations.
Area of Science:
- Medical Science
- Surgical Innovation
- Critical Care Medicine
Background:
- Obesity is linked to chronic inflammation, predisposing individuals to serious health issues like atherosclerosis, blood clots, cancer, and infections.
- Critically ill obese patients face higher mortality rates, with multiple organ failure (MOF) being a key predictor of intensive care unit (ICU) mortality.
- Pulmonary hypertension and elevated body mass index (BMI) are recognized as factors increasing surgical risk.
Purpose of the Study:
- To review the multifaceted health risks associated with obesity, including inflammatory states and surgical complications.
- To highlight the predictive value of multiple organ failure (MOF) in intensive care unit (ICU) mortality for obese patients.
- To assess the impact of advancements in surgical and anesthetic techniques on the safety of operating on severely obese individuals.
Main Methods:
- Literature review of studies on obesity, inflammation, critical illness, and surgical outcomes.
- Analysis of data correlating BMI, pulmonary hypertension, and surgical risk.
- Examination of trends in surgical techniques and anesthesia for obese patients.
Main Results:
- Obesity contributes to a pro-inflammatory state, elevating risks for atherogenesis, thrombogenesis, carcinogenesis, and infection susceptibility.
- Multiple organ failure (MOF) is identified as the primary predictor of ICU mortality in obese patients.
- Despite increased risks like pulmonary hypertension and higher BMI, surgical and anesthetic advancements have improved operative safety for severely obese patients.
Conclusions:
- Obesity presents significant health challenges due to chronic inflammation and increased critical care risks.
- While MOF predicts ICU mortality, advancements in surgical and anesthetic practices are making operations safer for the obese population.
- Continued research and technique refinement are crucial for mitigating surgical risks in severely obese patients.