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Neurologic complications of solid tumors.
1Division of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, 75 Francis St. Boston, MA 02115, USA. pwen@partners.org
Neurologic Clinics
|April 15, 2003
Summary
Neurologic complications are rising in patients with common solid tumors like lung and breast cancer due to improved cancer therapies. This review covers these increasing neurologic issues in various cancers.
Area of Science:
- Neuro-oncology
- Cancer medicine
- Clinical neurology
Background:
- Solid tumors frequently cause neurologic complications.
- Advances in systemic therapy are increasing patient survival rates.
- Consequently, the incidence of neurologic complications is on the rise.
Purpose of the Study:
- To review the spectrum of neurologic complications associated with common solid tumors.
- To highlight the increasing prevalence of these complications in the context of improved cancer treatments.
Main Methods:
- Comprehensive literature review of neurologic complications in major solid tumors.
- Analysis of the relationship between systemic therapy advancements and neurologic sequelae.
- Synthesis of current knowledge on diagnosis and management.
Main Results:
- Neurologic complications are a significant concern across lung, breast, gastrointestinal, genitourinary, gynecologic, head and neck cancers, melanoma, and sarcomas.
- Improved survival rates correlate with a higher observed incidence of neurological issues.
- Early recognition and management are crucial for patient outcomes.
Conclusions:
- Neurologic complications represent a growing challenge in oncology.
- Multidisciplinary approaches are essential for managing these complex cases.
- Further research is needed to optimize prevention and treatment strategies.