[Choice of renal replacement therapy in patients with complicated uremia]

Fourteen patients with complicated uremia and multiple organ dysfunction syndrome were treated by renal replacement therapy (RRT), by hemodialysis and hemodiafiltration. Control group consisted of 14 age-matched convalescents without clinical and laboratory signs of uremia and systemic inflammatory response syndrome. The potentialities of Integral Diagnostic Expert Analytical System (IDEAS) based on the spectrophotokinetic (SPK) technique (ECOTEST, Russia; Thermo Labsystems, Finland) were evaluated on the basis of objective evaluation of clinical condition of end-stage renal disease patients. SPK technology proved to be a highly informative method of automated diagnosis, which allows monitoring the dialysis efficiency, detecting combined diseases and poor system's biocompatibility, which, in turn, permits correction of the treatment and realization of a differentiated approach to the choice of RRT method.