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Sinonasal neurogenic tumours.

Pradeep Vaideeswar1, Chitra V Madiwale, Dimple Kathpal

  • 1Department of Pathology, Seth G S Medical College, Parel, Mumbai.

Indian Journal of Pathology & Microbiology
|April 17, 2003
PubMed
Summary

Neurogenic sinonasal tumors, including schwannomas and neurofibromas, represent 6.7% of cases. Malignant schwannomas require careful consideration in spindle cell lesions.

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Area of Science:

  • Otorhinolaryngology
  • Pathology
  • Surgical Oncology

Background:

  • Sinonasal tumors encompass a diverse group of neoplasms.
  • Neurogenic tumors are a less common but significant subset of sinonasal masses.

Purpose of the Study:

  • To analyze the incidence, presentation, and characteristics of neurogenic sinonasal tumors.
  • To highlight diagnostic considerations for malignant schwannomas in this region.

Main Methods:

  • Retrospective review of surgically excised or biopsied sinonasal tumors over a ten-year period.
  • Histopathological classification of identified neurogenic tumors.

Main Results:

  • Neurogenic tumors constituted 6.7% of all sinonasal tumors (eight cases).
  • The cohort included three schwannomas, two neurofibromas, and three malignant schwannomas.
  • Presentations commonly involved nasal obstruction and epistaxis, with unilateral location.
  • Wide age range and no gender predilection were observed.

Conclusions:

  • Benign neurogenic tumors are generally straightforward to diagnose.
  • Malignant schwannoma should be suspected in sinonasal cellular spindle cell lesions.

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