Signal transduction modulators for cancer therapy: from promise to practice?

Developments of MEK inhibitors as future cancer therapies: what have we learned from preclinical and clinical studies?

Expert opinion on investigational drugs·2025

Longitudinal Genomic Analysis of Five Cases of Recurrent Thymomas.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2025

Avelumab combined with axitinib for patients with advanced thymoma B3 and thymic carcinoma.

Cancer·2025

Heterogeneity of progression-free survival surrogacy by sex in randomized trials testing immunotherapy in non-small cell lung cancer.

JNCI cancer spectrum·2025

Digital Versus Manual PD-L1 Scoring in Advanced NSCLC From the IMpower110 and IMpower150 Trials.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2025

Parallel Phase II Clinical Trials of Selinexor in Patients With Advanced Thymoma and Thymic Carcinoma.

JTO clinical and research reports·2025

Use of real-world evidence in the U.S. Food and Drug Administration and the European Medicines Agency approvals of oncology products supported by single-arm trials (2022-2025).

The oncologist·2026

Osimertinib plus anlotinib in untreated, EGFR-mutated, advanced non-small-cell lung cancer with concurrent alterations: a multicenter phase II study.

The oncologist·2026

Paired genomic profiling of primary tumor and lymph-node metastases identifies candidate prognostic features in penile squamous cell carcinoma.

The oncologist·2026

Phase 2 Study of Futibatinib in Combination with Pembrolizumab in Patients with FGF19 expressing Advanced Hepatocellular Carcinoma.

The oncologist·2026

Bone health in advanced prostate cancer: pathophysiology and management strategies.

The oncologist·2026

Real-world efficacy and toxicity of tebentafusp in metastatic uveal melanoma patients treated on the United Kingdom expanded access programme.

The oncologist·2026

A marine-derived meroterpenoid inhibits colorectal cancer via PI3K pathway modulation in mice.

Marine life science & technology·2026

Noncoding RNA encoded peptides in tumors from discovery to mechanism and clinical translation.

iScience·2026

SGLT2 inhibitor therapy is associated with IL-10/TGF-α/sVEGFR3 signalling and adipose tissue remodelling in advanced heart failure.

Journal of molecular and cellular cardiology plus·2026

Efficacy and safety of SCT200 in patients with recurrent or metastatic head and neck squamous cell carcinoma after platinum failure: A phase 2 study.

Cancer pathogenesis and therapy·2026

Rapamycin Attenuates Acute Pancreatitis-Induced Acinar Injury in Mice With Pancreatic Loss of Gα13.

Gastro hep advances·2026

PTC124 promotes mutation site-dependent readthrough of STK11 nonsense mutations and restores tumor suppressor function.

BBA advances·2026

Related Experiment Videos

Signal transduction modulators for cancer therapy: from promise to practice?

Related Concept Videos

Developments of MEK inhibitors as future cancer therapies: what have we learned from preclinical and clinical studies?

Longitudinal Genomic Analysis of Five Cases of Recurrent Thymomas.

Avelumab combined with axitinib for patients with advanced thymoma B3 and thymic carcinoma.

Heterogeneity of progression-free survival surrogacy by sex in randomized trials testing immunotherapy in non-small cell lung cancer.

Digital Versus Manual PD-L1 Scoring in Advanced NSCLC From the IMpower110 and IMpower150 Trials.

Parallel Phase II Clinical Trials of Selinexor in Patients With Advanced Thymoma and Thymic Carcinoma.

Use of real-world evidence in the U.S. Food and Drug Administration and the European Medicines Agency approvals of oncology products supported by single-arm trials (2022-2025).

Osimertinib plus anlotinib in untreated, EGFR-mutated, advanced non-small-cell lung cancer with concurrent alterations: a multicenter phase II study.

Paired genomic profiling of primary tumor and lymph-node metastases identifies candidate prognostic features in penile squamous cell carcinoma.

Phase 2 Study of Futibatinib in Combination with Pembrolizumab in Patients with FGF19 expressing Advanced Hepatocellular Carcinoma.

Bone health in advanced prostate cancer: pathophysiology and management strategies.

Real-world efficacy and toxicity of tebentafusp in metastatic uveal melanoma patients treated on the United Kingdom expanded access programme.

A marine-derived meroterpenoid inhibits colorectal cancer via PI3K pathway modulation in mice.

Noncoding RNA encoded peptides in tumors from discovery to mechanism and clinical translation.

SGLT2 inhibitor therapy is associated with IL-10/TGF-α/sVEGFR3 signalling and adipose tissue remodelling in advanced heart failure.

Efficacy and safety of SCT200 in patients with recurrent or metastatic head and neck squamous cell carcinoma after platinum failure: A phase 2 study.

Rapamycin Attenuates Acute Pancreatitis-Induced Acinar Injury in Mice With Pancreatic Loss of Gα13.

PTC124 promotes mutation site-dependent readthrough of STK11 nonsense mutations and restores tumor suppressor function.

Related Experiment Videos

Signal transduction modulators for cancer therapy: from promise to practice?

Related Concept Videos

Related Articles