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Updated: Jan 10, 2026
09:01
Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
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[Hemicrania continua: the first Japanese case report]
Kumiko Ishizaki1, Takao Takeshima, Tamami Ijiri
1Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine.
Rinsho Shinkeigaku = Clinical Neurology
|April 19, 2003
Summary
A woman experienced severe, continuous unilateral headaches unresponsive to standard treatments. A daily dose of indomethacin completely resolved her symptoms, suggesting its potential use in similar refractory headache cases.
Area of Science:
- Neurology
- Clinical Medicine
- Pharmacology
Background:
- Chronic daily headaches present a significant challenge in clinical practice.
- Unilateral headaches with specific characteristics can be debilitating.
- Standard therapies often fail to provide relief for refractory headache conditions.
Observation:
- A 47-year-old female presented with strictly unilateral, continuous headache in the temporal-parietal region.
- The headache was described as 'jabs and jolts' with a pressing quality, fluctuating between moderate and severe intensity.
- Daily activities were significantly impaired due to the severity of the pain.
Findings:
- Treatment with a daily dose of 75 mg indomethacin led to complete resolution of the patient's headache.
- This case highlights the efficacy of indomethacin in a patient with chronic daily headache refractory to other treatments.
Implications:
- Indomethacin may be a valuable therapeutic option for patients with chronic daily headaches unresponsive to conventional therapies.
- Further investigation into indomethacin's role in managing specific types of refractory headaches is warranted.
- This case underscores the importance of considering alternative pharmacological agents when standard treatments fail.
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