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Updated: Jul 26, 2026
04:44
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Organizing pneumonia: prognostic implication of high-resolution computed tomography features.
Jin Seong Lee1, David A Lynch, Surit Sharma
1Department of Radiology, Health Sciences Center, University of Colorado School of Medicine, Denver, CO 80262, USA.
Journal of Computer Assisted Tomography
|April 19, 2003
Summary
High-resolution computed tomography (CT) can predict treatment response in organizing pneumonia (OP). Consolidation on initial CT suggests resolution, while reticular opacity indicates persistent disease.
Area of Science:
- Radiology
- Pulmonology
- Pathology
Background:
- Organizing pneumonia (OP) often resolves with treatment, but some cases progress to pulmonary fibrosis.
- Predicting treatment outcomes in OP is crucial for patient management.
Purpose of the Study:
- To investigate the prognostic value of high-resolution computed tomography (CT) findings in biopsy-proven organizing pneumonia (OP).
Main Methods:
- Retrospective review of high-resolution CT scans from 26 patients with histologically confirmed OP.
- Assessment of pretreatment CT features including ground-glass opacity, consolidation, nodules, reticular opacity, and honeycombing.
- Correlation of CT findings with radiographic follow-up to assess lesion regression or progression post-treatment.
Main Results:
- Consolidation on initial CT was significantly associated with lesion resolution (14/17 patients) compared to persistent disease (2/9 patients).
- Reticular opacity as the predominant pattern on initial CT was linked to a lack of complete resolution in all affected patients (6/6).
Conclusions:
- Initial CT findings of consolidation in organizing pneumonia (OP) predict a favorable treatment response with lesion resolution.
- The presence of reticular opacity on initial CT scans is indicative of persistent or progressive disease in patients with organizing pneumonia (OP).
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