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Updated: Aug 9, 2026
Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation
Published on: May 12, 2014
Non-supervised spatio-temporal analysis of interictal magnetic spikes: comparison with intracerebral recordings
D P Schwartz1, J M Badier, J P Vignal
1UPRES EA Cortex cérébral et Epilepsie, Université de Rennes 1, Rennes, France. denis.schwartz@chups.jussieu.fr
Objective:
Our main goal was to evaluate the accuracy of an original non-supervised spatio-temporal magnetoencephalography (MEG) localization method used to characterize interictal spikes generators.
Methods:
MEG and stereotactic intracerebral recordings (stereo-electro-encephalographic exploration, SEEG) data were analyzed independently in 4 patients. MEG localizations were performed with and without anatomical constraints.
Results:
We analyzed 1326 interictal spikes recorded using MEG. For each patient, 2-3 typical source patterns were described. These source configurations were compared with SEEG. SEEG findings and MEG spatio-temporal localization results were remarkably coherent in our 4 patients. Most of the MEG patterns were similar to interictal SEEG patterns from a spatio-temporal point of view.
Conclusions:
We were able to evaluate the usefulness of our non-invasive localization method. This approach described correctly the part of the epileptogenic network involved in the generation of interictal events. Our results demonstrate the potential of MEG in the non-invasive spatio-temporal characterization of generators of interictal spikes.
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