Related Experiment Video

Updated: Sep 26, 2026

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
08:30

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns

Published on: December 12, 2025

Epididymitis in infants with anorectal malformation

Gürsu Kiyan1, Tolga E Dagli, Serdar H Iskit

  • 1Department of Pediatric Surgery, Marmara University School of Medicine, Cocuk Cerrahisi Anabilim Dali, Tophanelioglu Caddesi 13-15, Altunizade, Istanbul, 81190, Turkey. gursukiyan@marmara.edu.tr

European Urology
|April 23, 2003
PubMed

Insights

Anorectal malformations in boys can cause epididymitis, particularly those with rectourethral fistulas. Urinary tract infections are linked to epididymitis in these patients, highlighting the need for comprehensive urological evaluation.

Area of Science:

  • Pediatric Urology
  • Surgical Gastroenterology

Background:

  • Anorectal malformations (ARM) are congenital conditions requiring surgical correction.
  • Epididymitis, inflammation of the epididymis, can occur in pediatric patients.
  • The association between ARM and epididymitis requires further characterization.

Purpose of the Study:

  • To document the clinical characteristics of epididymitis in boys diagnosed with anorectal malformations.
  • To investigate potential causes and associations of epididymitis in this specific patient population.

Main Methods:

  • Retrospective review of 66 boys with ARM treated between 1990-2000.
  • Analysis of four patients who experienced episodes of epididymitis.
  • Correlation of epididymitis occurrence with ARM type, presence of rectourethral fistula, and postoperative outcomes.

Main Results:

  • Three of four patients with ARM and rectourethral fistula experienced resolution of epididymitis after definitive surgery.
  • One patient with low-type ARM without fistula had recurrent postoperative epididymitis.
  • Urinary tract infection or contamination was noted in two patients during epididymitis episodes.

Conclusions:

  • Anorectal malformation, especially with a rectourethral fistula, is a potential cause of epididymitis in boys.
  • Associated urogenital anomalies may contribute to epididymitis in ARM patients.
  • A significant relationship exists between urinary tract infections and epididymitis in this cohort.
Abstract

More Related Videos

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst03:10

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia06:28

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

Related Concept Videos

Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...