Noninactivating tandem pore domain potassium channels as attractive targets for general anesthetics

Design and biophysical characterization of a monomeric four-alpha-helix bundle protein Aα₄ with affinity for the volatile anesthetic halothane.

Biochimica et biophysica acta·2012

Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, II: Fluorescence and vibrational spectroscopy using a cyanophenylalanine probe.

Biophysical journal·2009

Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, I: Structural investigations via X-ray reflectivity from Langmuir monolayers.

Biophysical journal·2009

Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses.

Biophysical journal·2008

Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics.

Biophysical journal·2008

Difficult airway management after carotid endarterectomy: utility and limitations of the Laryngeal Mask Airway.

Journal of clinical anesthesia·2007

A Multivariable Model of the Association Between Postoperative Complications and 30-Day In-Hospital Mortality in the African Surgical Outcome Study Cohort.

Anesthesia and analgesia·2026

A Double-Blinded Randomized Trial Comparing Dexamethasone to Ondansetron as the First-Line Antiemetic After Cesarean Delivery.

Anesthesia and analgesia·2026

Characteristics and Outcomes of Viral Sepsis: A Retrospective Study.

Anesthesia and analgesia·2026

Surgeon Incivility in the Preoperative Setting: A Multi-institutional Crossover Study on Anesthesiology Residents' Decision-Making.

Anesthesia and analgesia·2026

Association Between Extreme Weight-for-Age and Airway-Related Adverse Events During Anesthesia Induction: An Analysis Using the J-PEDIA Registry Data.

Anesthesia and analgesia·2026

Comparing brain absorption and lung deposition of nicotine salts and free-base e-cigarettes: insights from [11C]nicotine PET imaging.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026

Nano-Architectural Evolution and Hybridization Dynamics in Carbon Nanocoatings Under Electro-Mechanical Coupling.

Small (Weinheim an der Bergstrasse, Germany)·2026

Gas-permeable and stretchable nanoscale anisotropic conductive film for room-temperature, pressure-free interconnections.

Science advances·2026

Physics-Informed Graph Diffusion Model for Cross-Scale Performance Prediction of Silver Nanowire Percolation Networks.

ACS omega·2026

K2P channels as emerging therapeutic targets for pain: insights from functional studies and transcriptomic analyses.

Frontiers in pharmacology·2026

ECPR readiness without perfusionist support: a cross-sectional national survey on circuit preparation, team structure, and training.

BMC emergency medicine·2026

Related Experiment Videos

Noninactivating tandem pore domain potassium channels as attractive targets for general anesthetics

Related Concept Videos

Design and biophysical characterization of a monomeric four-alpha-helix bundle protein Aα₄ with affinity for the volatile anesthetic halothane.

Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, II: Fluorescence and vibrational spectroscopy using a cyanophenylalanine probe.

Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, I: Structural investigations via X-ray reflectivity from Langmuir monolayers.

Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses.

Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics.

Difficult airway management after carotid endarterectomy: utility and limitations of the Laryngeal Mask Airway.

A Multivariable Model of the Association Between Postoperative Complications and 30-Day In-Hospital Mortality in the African Surgical Outcome Study Cohort.

A Double-Blinded Randomized Trial Comparing Dexamethasone to Ondansetron as the First-Line Antiemetic After Cesarean Delivery.

Characteristics and Outcomes of Viral Sepsis: A Retrospective Study.

Surgeon Incivility in the Preoperative Setting: A Multi-institutional Crossover Study on Anesthesiology Residents' Decision-Making.

Association Between Extreme Weight-for-Age and Airway-Related Adverse Events During Anesthesia Induction: An Analysis Using the J-PEDIA Registry Data.

Comparing brain absorption and lung deposition of nicotine salts and free-base e-cigarettes: insights from [11C]nicotine PET imaging.

Nano-Architectural Evolution and Hybridization Dynamics in Carbon Nanocoatings Under Electro-Mechanical Coupling.

Gas-permeable and stretchable nanoscale anisotropic conductive film for room-temperature, pressure-free interconnections.

Physics-Informed Graph Diffusion Model for Cross-Scale Performance Prediction of Silver Nanowire Percolation Networks.

K2P channels as emerging therapeutic targets for pain: insights from functional studies and transcriptomic analyses.

ECPR readiness without perfusionist support: a cross-sectional national survey on circuit preparation, team structure, and training.

Related Experiment Videos

Noninactivating tandem pore domain potassium channels as attractive targets for general anesthetics

Related Concept Videos

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